Disfunção sexual em pacientes com transtorno afetivo bipolar: uma revisão sistemática

Abstract

Sexual dysfunction in patients with bipolar affective disorder: a systematic review. Background: Bipolar affective disorder (BD) is a chronic and prevalent psychiatric disorder, characterised by periods of depression and periods of abnormally elevated mood. It is a major cause of disability in the world, and can seriously harm patients’ quality of life, including sexuality and sexual activity. Aim: To review the literature to describe an association between sexual dysfunction (SD) and bipolar affective disorder. Methods: Systematic review in accordance with PRISMA criteria. The descriptors used were: "Bipolar Disorder" and "Sexual Disorder" or "Sexual Dysfunction". The search was conducted in LILACS, PubMed and SciELO. The articles which were published in English, Portuguese or Spanish, and addressed SD in patients with BD were selected. Results: 132 articles were identified, among which 10 were selected to complete reading and 4 were included for final analysis. Discussion: SD frequency in patients with BD is approximately 65%. There is an association between SD and psychoactive drugs, especially antipsychotic medications. Conclusions: It is necessary further clinical trials to establish an association between BD and SD.