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DC Field | Value | Language |
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dc.creator | Conceição, Sabrina Barbosa Matos da | - |
dc.date.accessioned | 2022-03-29T15:11:23Z | - |
dc.date.available | 2022-01-18 | - |
dc.date.available | 2022-03-29T15:11:23Z | - |
dc.date.issued | 2021-11-18 | - |
dc.identifier.uri | https://repositorio.ufba.br/handle/ri/34956 | - |
dc.description.abstract | Sickle cell anemia is one of the most common genetic diseases in Brazil, it is severe and its main clinical manifestations are painful crises and infection. An experimental study was carried out with the aim of evaluating the effectiveness of Laser Therapy (ILIB) in a follow-up service for patients with this disease in preventing these symptoms. The study included 81 individuals (21 cases/60 controls) with sickle cell anemia, over 12 years of age with body weight greater than or equal to 40 kg, who were receiving treatment at the Blood Center of Bahia in the period from October 2019 to March 2020 A clinical and laboratory examination and a semi-structured interview were conducted to obtain sociodemographic and clinical data. To assess quality of life, the WHOQOL-BREF was used before and after “Intravascular Laser Irradiation of Blood” (ILIB) laser therapy. The study was approved by the ethics committee - CAEE 16676619. 7. 1001.5013. Of the participants, 21 of the cases underwent laser therapy for 10 consecutive days and the care plan (interviews for the diagnosis, development of the care process and assessment of quality of life), and another 60 (control group) participated exclusively in the intervention of the care plan care. There was a significant difference between groups. ILIB contributed to improved sleep (p<0.0001) and decreased pain crises (p value <0.0355). There was no statistically significant difference in laboratory tests before and after ILIB in the case-assessed group. Regarding quality of life, there was an improvement in the psychological domain of the WHOQOL-BREF (p-value =0.001) between the case and control groups, with changes in life practices that intensified self-care and well-being. The intervention proved to be an adjunct in the treatment of sickle cell anemia, contributing to the prevention of painful symptoms and helping to improve quality of life. | pt_BR |
dc.description.sponsorship | FAPESB | pt_BR |
dc.language | por | pt_BR |
dc.publisher | Universidade Federal da Bahia | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.subject | Irradiação de sangue intravascular com laser | pt_BR |
dc.subject | Anemia Falciforme | pt_BR |
dc.subject | Dor | pt_BR |
dc.subject | Intravascular Laser Irradiation of Blood | pt_BR |
dc.subject.other | Sickle Cell Anemia | pt_BR |
dc.subject.other | Ache | pt_BR |
dc.title | Análise da efetividade da hemolaserterapia para prevenção da sintomatologia dolorosa, alterações hematológicas e impacto na qualidade de vida em pacientes com anemia falciforme | pt_BR |
dc.title.alternative | Analysis of the effectiveness of hemolasertherapy for the prevention of symptomatology pain, hematological changes and impact on quality of life in patients with sickle cell anemia | pt_BR |
dc.type | Tese | pt_BR |
dc.publisher.program | Programa de Pós-Graduação em Biotecnologia Rede Nordeste (Renorbio) | pt_BR |
dc.publisher.initials | UFBA | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.subject.cnpq | CNPQ::OUTROS | pt_BR |
dc.contributor.advisor1 | Cangussu, Maria Cristina Teixeira | - |
dc.contributor.advisor1ID | https://orcid.org/0000-0001-9295-9486 | pt_BR |
dc.contributor.advisor1Lattes | http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4763789Z3&tokenCaptchar=03AGdBq25YaysGgIqRhFYVKIu8N4g-B6aekTDGhJ-6lGRCajils2TzYumMd7TPD5JJM0KgQOo2ldCWyumKMiTsFUy_Rsf4aMjzxwmGjvkeQ_23wBjx3GhvfhpImwpleGdMMO0mjLTJRdttaghtJ1VOyPmz3gqd-2Nok9D41-YWtOdYSgJBMQo-zl5piB4p4zSibNSBLjQhE7S8uwV5XASC30EnRnXAQYYIvgXlG7goY_NfL-ftrCFNHYS-YoUmh4IQt98oAVkp2c2mvuy5yE3zbOZCutZK2h_MQRzm1TEu0tMf_Qr7RYBUWf0oWsXTiTqd3omSXbb38rsTBbUC_JP1v1Ty-7fjvFyc8hahhSbaAq01m_Tbq_PYI8LFKhLpTHg7aASifjBGSsUhhMs2P-5Cdg3HRoLbogiAKODXKgO0EO0UYL3Moca8JfjwrhP_wA2AB1aAISTHC1svY4NwWDuArqpXYhFRDdAeLw | pt_BR |
dc.contributor.referee1 | Cangussu, Maria Cristina Teixeira | - |
dc.contributor.referee1ID | http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4763789Z3&tokenCaptchar=03AGdBq2 | pt_BR |
dc.contributor.referee1Lattes | https://orcid.org/0000-0001-9295-9486 | pt_BR |
dc.contributor.referee2 | Pinheiro, Antonio Luiz Barbosa | - |
dc.contributor.referee2ID | https://orcid.org/0000-0002-5805-0321 | pt_BR |
dc.contributor.referee2Lattes | http://lattes.cnpq.br/5840732667923853 | pt_BR |
dc.contributor.referee3 | Crugeira, Pedro Jorge Louro | - |
dc.contributor.referee3ID | https://orcid.org/0000-0002-7084-3711 | pt_BR |
dc.contributor.referee3Lattes | http://lattes.cnpq.br/2973332474703806 | pt_BR |
dc.contributor.referee4 | Sampaio, Fernando Jose Pires | - |
dc.contributor.referee4Lattes | http://lattes.cnpq.br/2221737061645417 | pt_BR |
dc.contributor.referee5 | Mota, Clarice Santos | - |
dc.contributor.referee5ID | https://orcid.org/0000-0002-5168-7004 | pt_BR |
dc.contributor.referee5Lattes | http://lattes.cnpq.br/0237744521147975 | pt_BR |
dc.creator.ID | https://orcid.org/0000-0002-3275-2210 | pt_BR |
dc.creator.Lattes | http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4480673D4&tokenCaptchar=03AGdBq27OKARktKxpjMPzvaIlTVU4jvMF63ce5K8BM-xZlOjkel-WrHjZQ27Ehn8xUowcroh0pk3AFum6ZxT2y5LMLTFrU7K2PZhDFpFsNiXcuxDCQtqslIRv2ACHzzwk9RLjxgjS0Fbjv6MEEOXqskqLiItB2jDu4Q956qeqjIFN5tvd_Gl_eM_3LSuYb9zRdRuutUckeDHGngmj_txnQOjZ5GzJsX1DHJSB7hz19pYUns1-uEdcl9R15JR7if-0d669QwKY1h21NSd45ZJqKJ5qvn5Cru5VA7gFgqXgCOpoVBISELmPcIhQYlyMewW35HRMZjF8FPrengx4PnnnVBtFHvhWkTIlI33_Lc0JNfXZ-c_18e195jJmqt9dojpghjgiNu10gEHJJZIDi3hEimmBV6OeYYkxmIXKjZJzdT7hgFj25kW3qRbI9CrrIUO-9s9-h1mYH9GESz8-TmIDW0lHzz9KKfBHBg | pt_BR |
dc.description.resumo | A anemia falciforme é uma das doenças genéticas mais comuns no Brasil, grave e suas principais manifestações clínicas são as crises dolorosas e quadros de infecção. Realizou-se um estudo experimental com o objetivo de analisar a efetividade da Hemolaserterapia (ILIB) em serviço de acompanhamento a pacientes com esta doença na prevenção destes sintomas. Foram incluídos no estudo 81 indivíduos (21 casos/ 60 controles) com anemia falciforme, maiores de 12 anos de idade com peso corporal acima ou igual a 40 quilos, que recebiam tratamento no Hemocentro da Bahia no período de outubro de 2019-março de 2020. Conduziuse exame clínico, laboratoriais e entrevista semiestruturada para obtenção de dados sociodemográficos e clínicos. Para avaliação da qualidade de vida foi utilizado o WHOQOLBREF antes e após a hemolaserterapia “Intravascular Laser Irradiation of Blood” (ILIB). O estudo foi aprovado pelo comitê de ética- CAEE 16676619.7.1001.5013. Dos participantes, 21 dos casos realizaram hemolaserterapia por 10 dias consecutivos e o plano de cuidados (entrevistas para o diagnóstico, desenvolvimento do processo de cuidado e avaliação da qualidade de vida), e outros 60 (grupo controle) participaram exclusivamente da intervenção do plano de cuidados. Houve diferença significativa entre os grupos. O ILIB contribuiu para melhora do sono (p<0,0001) e diminuição das crises de dor (p valor <0,0355). Não houve diferença estatisticamente significativa nos exames laboratoriais antes e após ILIB no grupo caso avaliado. Em relação a qualidade de vida, houve melhora no domínio psicológico do WHOQOL- BREF (p-valor =0,001) entre os grupos caso e controle, com mudanças nas práticas de vida que intensificaram o autocuidado e bem-estar. A intervenção mostrou-se adjuvante no tratamento da anemia falciforme, podendo contribuir na prevenção de sintomatologia dolorosa e contribuindo para melhorar a qualidade de vida. | pt_BR |
dc.publisher.department | Instituto de Ciências da Saúde - ICS | pt_BR |
Appears in Collections: | Tese (Renorbio) |
Files in This Item:
File | Description | Size | Format | |
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Tese de Doutorado versão final - Sabrina Barbosa.pdf | 5,69 MB | Adobe PDF | View/Open |
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