Use este identificador para citar ou linkar para este item:
https://repositorio.ufba.br/handle/ri/19049
Registro completo de metadados
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Cardoso, Cristiane Wanderley | - |
dc.contributor.author | Ribeiro, Guilherme Sousa | - |
dc.contributor.author | Reis, Mitermayer Galvão | - |
dc.contributor.author | Flannery, Brendan | - |
dc.contributor.author | Reis, Joice Neves | - |
dc.creator | Cardoso, Cristiane Wanderley | - |
dc.creator | Ribeiro, Guilherme Sousa | - |
dc.creator | Reis, Mitermayer Galvão | - |
dc.creator | Flannery, Brendan | - |
dc.creator | Reis, Joice Neves | - |
dc.date.accessioned | 2016-05-03T17:30:47Z | - |
dc.date.available | 2016-05-03T17:30:47Z | - |
dc.date.issued | 2015-04 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://repositorio.ufba.br/ri/handle/ri/19049 | - |
dc.description.abstract | During a citywide epidemic of serogroup C meningococcal disease in Salvador in 2010, Brazil, the state government initiated mass vaccination targeting two age groups with high attack rates: individuals aged <5 years and 10–24 years. More than 600,000 doses of meningococcal serogroup C conjugate vaccines were administered. We performed a casecontrol study to evaluate vaccine uptake, document vaccine effectiveness and identify reasons for non-vaccination. Methods and Findings Population-based surveillance identified patients with laboratory-confirmed invasive meningococcal C (MenC) disease during 2010. Information on MenC vaccination was obtained from case patients and age-matched individuals from the same neighborhoods. MenC vaccine effectiveness was estimated based on the exact odds ratios obtained by conditional logistic regression analysis. Of 51 laboratory-confirmed cases of serogroup C meningococcal disease among patients <5 and 10–24 years of age 50 were included in the study and matched with 240 controls. Overall case-fatality was 25%.MenC vaccine coverage among controls increased from 7.1%to 70.2% after initiation of the vaccination campaign. None of the 50 case patients but 70 (29.2%) of the 240 control individuals, including 59 (70.2%) of 84 matched with cases from the period afterMenC vaccination, had received at least one MenC vaccine dose. Overall effectiveness of MenC was 98%with a lower 95%exact confidence limit of 89%. Conclusions MenC vaccines administered during the meningococcal epidemic were highly effective, suggesting that rapid vaccine uptake through campaigns contributed to control of meningococcal disease. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | Public Library of Science | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.source | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395143/pdf/pone.0123734.pdf | pt_BR |
dc.subject | Meningococcal Disease | pt_BR |
dc.subject | Meningococcal Vaccine | pt_BR |
dc.subject | Epidemic | pt_BR |
dc.title | Effectiveness of Meningococcal C conjugate vaccine in Salvador, Brazil: a case-control study. | pt_BR |
dc.title.alternative | PLoS One | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.description.localpub | San Francisco | pt_BR |
dc.identifier.number | v.10, n.4, p.1-12 | pt_BR |
dc.publisher.country | Brasil | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico Estrangeiro (ISC) |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Art Per Estrang Guilherme Ribeiro3. 2015.pdf | 188,33 kB | Adobe PDF | Visualizar/Abrir |
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.