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Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/16188
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dc.contributor.authorOliveira, Ricardo Riccio-
dc.contributor.authorFigueiredo, Joanemile Pacheco de-
dc.contributor.authorCardoso, Luciana Santos-
dc.contributor.authorJabar, Rafael L.-
dc.contributor.authorSouza, Robson da Paixão de-
dc.contributor.authorWells, Martin T.-
dc.contributor.authorCarvalho Filho, Edgar Marcelino de-
dc.contributor.authorFitzgerald, Daniel W.-
dc.contributor.authorBarnes, Kathleen C.-
dc.contributor.authorAraujo, Maria Ilma Andrade Santos-
dc.contributor.authorGlesby, Marshall J.-
dc.creatorOliveira, Ricardo Riccio-
dc.creatorFigueiredo, Joanemile Pacheco de-
dc.creatorCardoso, Luciana Santos-
dc.creatorJabar, Rafael L.-
dc.creatorSouza, Robson da Paixão de-
dc.creatorWells, Martin T.-
dc.creatorCarvalho Filho, Edgar Marcelino de-
dc.creatorFitzgerald, Daniel W.-
dc.creatorBarnes, Kathleen C.-
dc.creatorAraujo, Maria Ilma Andrade Santos-
dc.creatorGlesby, Marshall J.-
dc.date.accessioned2014-09-29T14:14:42Z-
dc.date.issued2012-
dc.identifier.issn0002-9637-
dc.identifier.urihttp://repositorio.ufba.br/ri/handle/ri/16188-
dc.descriptionTexto completo: acesso restrito. p. 296-305pt_BR
dc.description.abstractDetailed knowledge of factors associated with resistance to Schistosoma mansoni infection in endemic areas might facilitate more effective schistosomiasis control. We conducted a cross-sectional study of persons resistant to schistosomiasis and found no association between socioeconomic status and resistance to infection. Mononuclear cells of resistant subjects produced higher levels of interleukin-5 (IL-5), IL-13 and interferon-γ upon stimulation with soluble egg antigen (SEA) compared with infected persons. When stimulated with Sm21.6 or Sm22.6, levels of IL-10 were higher in cell culture of resistant persons. Levels of IgE against soluble adult worm antigen (SWAP) and against interleukin-4–inducing principle from S. mansoni eggs (IPSE) and levels of IgG4 against SWAP, SEA, and Sm22.6 were lower in the resistant group compared with the susceptible group. Our data suggest that socioeconomic status could not fully explain resistance to S. mansoni infection observed in the studied area. However, a mixture of Th1 and Th2 immune responses and low levels of specific IgG4 against parasite antigens could be mediating resistance to infection.pt_BR
dc.language.isoenpt_BR
dc.rightsAcesso Abertopt_BR
dc.sourcehttp://dx.doi.org/ 10.4269/ajtmh.2012.11-0204pt_BR
dc.subjectSchistosoma mansonipt_BR
dc.titleFactors Associated with Resistance to Schistosoma mansoni Infection in an Endemic Area of Bahia, Brazilpt_BR
dc.title.alternativeAmerican Journal of Tropical Medicine and Hygienept_BR
dc.typeArtigo de Periódicopt_BR
dc.identifier.numberv. 86, n. 2pt_BR
dc.embargo.liftdate10000-01-01-
Aparece nas coleções:Artigo Publicado em Periódico (Faculdade de Medicina)

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