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Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/15609
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dc.contributor.authorMatta, José Alberto Martins da-
dc.contributor.authorAras Júnior, Roque-
dc.contributor.authorMacedo, Cristiano Ricardo Bastos de-
dc.contributor.authorCruz, Cristiano Gonçalves da-
dc.contributor.authorMartins Netto, Eduardo-
dc.creatorMatta, José Alberto Martins da-
dc.creatorAras Júnior, Roque-
dc.creatorMacedo, Cristiano Ricardo Bastos de-
dc.creatorCruz, Cristiano Gonçalves da-
dc.creatorMartins Netto, Eduardo-
dc.date.accessioned2014-08-13T16:11:16Z-
dc.date.issued2013-
dc.identifier.issn1932-6203-
dc.identifier.urihttp://repositorio.ufba.br/ri/handle/ri/15609-
dc.descriptionp. 1-7pt_BR
dc.description.abstractBackground Aging and migration have brought changes to the epidemiology and stroke has been shown to be independently associated with Chagas disease. We studied stroke correlates in cardiomyopathy patients with focus on the chagasic etiology. Methodology/Principal Findings We performed a cross-sectional review of medical records of 790 patients with a cardiomyopathy. Patients with chagasic (329) and non-chagasic (461) cardiomyopathies were compared. There were 108 stroke cases, significantly more frequent in the Chagas group (17.3% versus 11.1%; p<0.01). Chagasic etiology (odds ratio [OR], 1.79), pacemaker (OR, 2.49), atrial fibrillation (OR, 3.03) and coronary artery disease (OR, 1.92) were stroke predictors in a multivariable analysis of the entire cohort. In a second step, the population was split into those with or without a Chagas-related cardiomyopathy. Univariable post-stratification stroke predictors in the Chagas cohort were pacemaker (OR, 2.73), and coronary artery disease (CAD) (OR, 2.58); while atrial fibrillation (OR, 2.98), age over 55 (OR, 2.92), hypertension (OR, 2.62) and coronary artery disease (OR, 1.94) did so in the non-Chagas cohort. Chagasic stroke patients presented a very high frequency of individuals without any vascular risk factors (40.4%; OR, 4.8). In a post-stratification logistic regression model, stroke remained associated with pacemaker (OR, 2.72) and coronary artery disease (OR, 2.60) in 322 chagasic patients, and with age over 55 (OR, 2.38), atrial fibrillation (OR 3.25) and hypertension (OR 2.12; p = 0.052) in 444 non-chagasic patients. Conclusions/Significance Chagas cardiomyopathy presented both a higher frequency of stroke and an independent association with it. There was a high frequency of strokes without any vascular risk factors in the Chagas as opposed to the non-Chagas cohort. Pacemaker rhythm and CAD were independently associated with stroke in the Chagas group while age over 55 years, hypertension and atrial fibrillation did so in the non-Chagas cardiomyopathies.pt_BR
dc.language.isoenpt_BR
dc.rightsAcesso Abertopt_BR
dc.sourcehttp://dx.doi.org/ 10.1371/journal.pone.0035116pt_BR
dc.titleStroke Correlates in Chagasic and Non-Chagasic Cardiomyopathiespt_BR
dc.title.alternativePLoS ONEpt_BR
dc.typeArtigo de Periódicopt_BR
dc.identifier.numberv. 7, n. 4pt_BR
dc.embargo.liftdate10000-01-01-
Aparece nas coleções:Artigo Publicado em Periódico (Faculdade de Medicina)

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