https://repositorio.ufba.br/handle/ri/15572
metadata.dc.type: | Artigo de Periódico |
Title: | Hantavirus pulmonary syndrome: Prognostic factors for death in reported cases in Brazil |
Other Titles: | Transactions of The Royal Society of Tropical Medicine and Hygiene |
Authors: | Dias, Juarez Pereira Elkhoury, Mauro da Rosa Mendes, Wellington da Silva Waldman, Eliseu Alves Carmo, Eduardo Hage Vasconcelos, Pedro Fernando da Costa |
metadata.dc.creator: | Dias, Juarez Pereira Elkhoury, Mauro da Rosa Mendes, Wellington da Silva Waldman, Eliseu Alves Carmo, Eduardo Hage Vasconcelos, Pedro Fernando da Costa |
Abstract: | Hantavirus pulmonary syndrome (HPS) was described for the first time in Brazil in 1993 and has occurred endemically throughout the country. This study analysed clinical and laboratory aspects as well as death-related factors for HPS cases in Brazil from 1993 to 2006. The investigation comprised a descriptive and exploratory study of the history of cases as well as an analytical retrospective cohort survey to identify prognostic factors for death due to HPS. A total of 855 Brazilian HPS cases were assessed. The majority of cases occurred during spring (33.5%) and winter (27.6%), mainly among young male adults working in rural areas. The global case fatality rate was 39.3%. The mean interval between the onset of symptoms and hospitalisation was 4 days and that between hospitalisation and death was 1 day. In the multiple regression analysis, adult respiratory distress syndrome and mechanical respiratory support were associated with risk of death; when these two variables were excluded from the model, dyspnoea and haemoconcentration were associated with a higher risk of death. |
Keywords: | Hantavirus Hantavirus pulmonary syndrome Epidemiology Prognostic factors Brazil |
metadata.dc.rights: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/15572 |
Issue Date: | 2012 |
Appears in Collections: | Artigo Publicado em Periódico Estrangeiro (ISC) |
File | Description | Size | Format | |
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Juarez Pereira Dias.pdf | 204,42 kB | Adobe PDF | View/Open |
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