Skip navigation
Universidade Federal da Bahia |
Repositório Institucional da UFBA
Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/15043
Registro completo de metadados
Campo DCValorIdioma
dc.contributor.authorDrexler, Jan Felix-
dc.contributor.authorGrywna, Klaus-
dc.contributor.authorLukashev, Alexander-
dc.contributor.authorAlmeida, Patrícia Silva-
dc.contributor.authorRibeiro, Tereza Cristina Medrado-
dc.contributor.authorPetersen, Nadine-
dc.contributor.authorRibeiro Jr, Hugo da Costa-
dc.contributor.authorBelalov, Ilya-
dc.contributor.authorKümmerer, Beate Mareike-
dc.creatorDrexler, Jan Felix-
dc.creatorGrywna, Klaus-
dc.creatorLukashev, Alexander-
dc.creatorAlmeida, Patrícia Silva-
dc.creatorRibeiro, Tereza Cristina Medrado-
dc.creatorPetersen, Nadine-
dc.creatorRibeiro Jr, Hugo da Costa-
dc.creatorBelalov, Ilya-
dc.creatorKümmerer, Beate Mareike-
dc.date.accessioned2014-06-02T13:18:08Z-
dc.date.issued2011-
dc.identifier.issn0022-1317-
dc.identifier.urihttp://repositorio.ufba.br/ri/handle/ri/15043-
dc.descriptionTexto completo: acesso restrito. p. 564-571pt_BR
dc.description.abstractDue to high genome plasticity, the evolutionary fate and geographical history of picornaviruses is hard to follow. Here, we determined the complete coding sequences of eight human parechoviruses (HPeV) of types 1, 5 and 6 directly from clinical samples from Brazil. The capsid genes of these strains were not remarkably different from European, North American and Japanese HPeV. Full genome analysis revealed frequent intertypic recombination in the non-structural genome region. In addition, evidence of recombination between viruses of the same type in the capsid-encoding genome region among HPeV1 and HPeV4 was obtained. Bayesian phylogenetic analysis indicated that strains without evidence of recombination with each other in any genome region were separated by no more than 35 years of circulation. Interestingly, in the 3C gene, all Brazilian parechoviruses grouped together regardless of serotype. The most recent common ancestor of these strains dated back 108 years, suggesting long-term endemicity of this particular P3 genome lineage in South America. Our results support the idea that picornavirus replicative genes acquire capsid proteins introduced by new strains. Under certain epidemiological conditions, replicative genes may be maintained in circumscript geographical regions.pt_BR
dc.language.isoenpt_BR
dc.rightsAcesso Abertopt_BR
dc.sourcehttp://dx.doi.org/ 10.1099/vir.0.022525-0pt_BR
dc.subjectPicornaviridae infectionspt_BR
dc.subjectCapsid proteinspt_BR
dc.subjectGenespt_BR
dc.titleFull genome sequence analysis of parechoviruses from Brazil reveals geographical patterns in the evolution of non-structural genes and intratypic recombination in the capsid regionpt_BR
dc.title.alternativeJournal of General Virologypt_BR
dc.typeArtigo de Periódicopt_BR
dc.identifier.numberv. 92, n. 3pt_BR
dc.embargo.liftdate10000-01-01-
Aparece nas coleções:Artigo Publicado em Periódico (Faculdade de Medicina)

Arquivos associados a este item:
Arquivo Descrição TamanhoFormato 
Jan Felix Drexler.pdf604,76 kBAdobe PDFVisualizar/Abrir
Mostrar registro simples do item Visualizar estatísticas


Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.