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Campo DC | Valor | Idioma |
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dc.contributor.author | Luz, C. P. | - |
dc.contributor.author | Souza, A. | - |
dc.contributor.author | Reis, R. | - |
dc.contributor.author | Mineiro, P. | - |
dc.contributor.author | Ferreira, Hilda Silva | - |
dc.contributor.author | Fregoneze, J. B. | - |
dc.contributor.author | Silva, E. De Castro e | - |
dc.creator | Luz, C. P. | - |
dc.creator | Souza, A. | - |
dc.creator | Reis, R. | - |
dc.creator | Mineiro, P. | - |
dc.creator | Ferreira, Hilda Silva | - |
dc.creator | Fregoneze, J. B. | - |
dc.creator | Silva, E. De Castro e | - |
dc.date.accessioned | 2014-02-06T20:10:30Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0006-8993 | - |
dc.identifier.uri | http://repositorio.ufba.br/ri/handle/ri/14551 | - |
dc.description | Texto completo: acesso restrito. p. 178-194 | pt_BR |
dc.description.abstract | In the present paper, we have evaluated the participation of 5-HT3 and 5-HT2C receptors in the central amygdala (CeA) in the regulation of water and salt intake in sodium-depleted rats. m-CPBG-induced pharmacological activation of 5-HT3 receptors located in the CeA resulted in a significant reduction in salt intake in sodium-depleted rats. This antinatriorexic effect of m-CPBG was reverted by pretreatment with the selective 5-HT3 receptor antagonist ondansetron. The injection of ondansetron alone into the CeA had no effect on sodium-depleted and normonatremic rats. Conversely, pharmacological stimulation of 5-HT2C receptors located in the central amygdala by the selective 5-HT2C receptor agonist m-CPP failed to modify salt intake in sodium-depleted rats. Additionally, the administration of a selective 5-HT2C receptor blocker, SDZ SER 082, failed to modify salt intake in rats submitted to sodium depletion. These results lead to the conclusion that the pharmacological activation of 5-HT3 receptors located within the CeA inhibits salt intake in sodium-depleted rats and that 5-HT2C receptors located within the CeA appear to be dissociated from the salt intake control mechanisms operating in the central amygdala. | pt_BR |
dc.language.iso | en | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.source | http://dx.doi.org/10.1016/j.brainres.2007.01.012 | pt_BR |
dc.subject | Serotonin | pt_BR |
dc.subject | 5HT2 receptor | pt_BR |
dc.subject | 5HT3 receptor | pt_BR |
dc.subject | Salt intake | pt_BR |
dc.subject | Water intake | pt_BR |
dc.subject | Thirst | pt_BR |
dc.subject | Amygdala | pt_BR |
dc.subject | Central amygdala | pt_BR |
dc.title | The central amygdala regulates sodium intake in sodium-depleted rats: role of 5-HT3 and 5-HT2C receptors | pt_BR |
dc.title.alternative | Brain Research | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 1139, n. 1 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (ICS) |
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Arquivo | Descrição | Tamanho | Formato | |
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1-s2.0-S0006899307000340-main.pdf | 2,47 MB | Adobe PDF | Visualizar/Abrir |
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