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Campo DC | Valor | Idioma |
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dc.contributor.author | Medeiros Junior, Manoel | - |
dc.contributor.author | Figueiredo, Joanemile Pacheco de | - |
dc.contributor.author | Almeida, Maria Cecília Freitas de | - |
dc.contributor.author | Matos, Maria Analia | - |
dc.contributor.author | Araujo, Maria Ilma Andrade Santos | - |
dc.contributor.author | Cruz Filho, Álvaro Augusto Souza da | - |
dc.contributor.author | Atta, Ajax Mercês | - |
dc.contributor.author | Rêgo, Marco Antônio Vasconcelos | - |
dc.contributor.author | Jesus, Amélia Maria Ribeiro de | - |
dc.contributor.author | Taketomi, Ernesto Akio | - |
dc.contributor.author | Carvalho Filho, Edgar Marcelino de | - |
dc.creator | Medeiros Junior, Manoel | - |
dc.creator | Figueiredo, Joanemile Pacheco de | - |
dc.creator | Almeida, Maria Cecília Freitas de | - |
dc.creator | Matos, Maria Analia | - |
dc.creator | Araujo, Maria Ilma Andrade Santos | - |
dc.creator | Cruz Filho, Álvaro Augusto Souza da | - |
dc.creator | Atta, Ajax Mercês | - |
dc.creator | Rêgo, Marco Antônio Vasconcelos | - |
dc.creator | Jesus, Amélia Maria Ribeiro de | - |
dc.creator | Taketomi, Ernesto Akio | - |
dc.creator | Carvalho Filho, Edgar Marcelino de | - |
dc.date.accessioned | 2014-01-28T14:34:06Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0091-6749 | - |
dc.identifier.uri | http://repositorio.ufba.br/ri/handle/ri/14491 | - |
dc.description | Texto completo: acesso restrito. p. 947–951 | pt_BR |
dc.description.abstract | Background: Helminthic infections decrease skin reactivity to indoor allergens, but data on whether they influence asthma severity are lacking. Objective: This study evaluated the course of asthma in patients with and without Schistosoma mansoni infection. Methods: Asthmatic subjects were enrolled from 3 low-socioeconomic areas: a rural area endemic for schistosomiasis (group 1) in addition to a rural area (group 2) and a slum area (group 3), both of which were not endemic for schistosomiasis. A questionnaire on the basis of the International Study of Asthma and Allergies in Childhood study was applied in these 3 areas, and from each area, 21 age- and sex-matched asthmatic subjects were selected for a prospective 1-year study. Pulmonary function tests, skin prick tests with indoor allergens, stool examinations, and serum evaluations were performed in these subjects. Every 3 months, the subjects were evaluated for asthma exacerbation through physical examination, and a questionnaire regarding asthma symptoms and use of antiasthma medicine was administered. Results: The prevalence of S mansoni infection was greater in group 1 compared with in groups 2 and 3 (P < .0001), whereas the frequency of other helminth and protozoa infections was similar among the 3 groups. The frequency of positive skin test responses to indoor allergens was less (19.0%) in group 1 subjects relative to those in group 2 (76.2%) and group 3 (57.1%; P < .001). The frequencies of symptoms, use of antiasthma drugs, and pulmonary abnormal findings at physical examination were less in group 1 subjects than in group 2 and 3 subjects (P = .0001). Conclusion: Our results suggest that S mansoni infection is associated with a milder course of asthma. | pt_BR |
dc.language.iso | en | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.source | http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1067/mai.2003.1381 | pt_BR |
dc.subject | Asthma | pt_BR |
dc.subject | Skin prick test | pt_BR |
dc.subject | Dust mites | pt_BR |
dc.subject | Helminths | pt_BR |
dc.subject | Schistosoma mansoni | pt_BR |
dc.subject | IL-10 | pt_BR |
dc.subject | IgE | pt_BR |
dc.title | Schistosoma mansoni infection is associated with a reduced course of asthma | pt_BR |
dc.title.alternative | Journal of Allergy and Clinical Immunology | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 111, n. 5 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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Manoel Medeiros Jr..pdf | 87,23 kB | Adobe PDF | Visualizar/Abrir |
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