https://repositorio.ufba.br/handle/ri/14280
Tipo: | Artigo de Periódico |
Título: | Majority of Interferon-g–Producing CD4+ Cells in Patients Infected with Human T Cell Lymphotrophic Virus Do Not Express Tax Protein |
Título(s) alternativo(s): | Journal of Infectious Diseases |
Autor(es): | Carvalho Filho, Edgar Marcelino de Mitre, Edward Thompson, Robert W. Nutman, Thomas B. Neva, Franklin A. |
Autor(es): | Carvalho Filho, Edgar Marcelino de Mitre, Edward Thompson, Robert W. Nutman, Thomas B. Neva, Franklin A. |
Abstract: | The present study was conducted to determine whether interferon (IFN)-γ production by CD4+ cells in patients infected with human T cell lymphotropic virus (HTLV) is associated with expression of Tax, an HTLV type 1 (HTLV-1) transactivator. The frequency of IFN-γ production from CD4+ cells was greater in HTLV-1-infected patients (n = 21) than in uninfected (n = 3) and Strongyloides stercoralis-infected patients (n = 4), and greater in patients with HTLV-1 with detectable Tax than in patients with HTLV-1 with undetectable Tax. In the patients with HTLV-1 with detectable Tax, the majority of CD4+ cells making IFN-γ did not express Tax. |
Palavras-chave: | Human T Cell Lymphotrophic Virus Gene Products, tax CD4 + Cells Human T-lymphotropic virus 1 |
Tipo de Acesso: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/14280 |
Data do documento: | 2003 |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Arquivo | Descrição | Tamanho | Formato | |
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Edgar M. Carvalho.pdf | 129,46 kB | Adobe PDF | Visualizar/Abrir |
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