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Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/13837
Tipo: Artigo de Periódico
Título: Serological markers of hepatitis A, B and C viruses in rural communities of the semiarid Brazilian Northeast
Título(s) alternativo(s): Brazilian Journal of Infectious Diseases
Autor(es): Almeida, Delvone
Tavares-Neto, José
Vitvitski, Ludmila
Almeida, Alessandro
Mello, Caroline
Santana, Diana
Tatsch, Fernando
Paraná, Raymundo
Autor(es): Almeida, Delvone
Tavares-Neto, José
Vitvitski, Ludmila
Almeida, Alessandro
Mello, Caroline
Santana, Diana
Tatsch, Fernando
Paraná, Raymundo
Abstract: In the village of Cavunge, located in a dry tropical, semiarid rural region of the state of Bahia, Brazil, a sentinel study on viral hepatitis is underway. We report on the first part of the study. The objective of this study was to determine the prevalence of serological markers for hepatitis A, B and C in the village. Cross sectional study. Blood samples were tested for serological markers of hepatitis A (HAV), B (HBV) and C (HCV) through ELISA-III assay. In HBsAg and anti-HCV carriers, HCV-RNA and HBV-DNA were checked by PCR. The prevalence of anti-HAV IgG was 83.3% (1,210/1,452), being higher among residents from the village (87.4%) than in residents from the rural area (79.5%); it also higher among individuals older than 10 years of age. The prevalence of HBsAg was 2.6% (38/1,476), 9.3% anti-HBc (137/1,476) and 10.5% (155/1,476) anti-HBs of. In more than half (58.1%; 90/155) of anti-HBs carriers, this was the only serological marker found. In 3.7% of the population, (55/1,476), anti-HBc was the only serological marker found. All HBV carriers were infected by genotype A. Only 0.4% (6/1,536) presented anti-HCV antibodies and only one of them was viremic, being infected with genotype 1. The prevalence of patients with antibodies against hepatitis A virus in the village of Cavunge was high, but the prevalence of B virus was moderate, with only genotype A among HBV carriers. The prevalence of C virus was very low, contrasting with the situation in large Brazilian urban centers.
Palavras-chave: Hepatitis A
Hepatitis B
Hepatitis C
Epidemiology
Tipo de Acesso: Acesso Aberto
URI: http://repositorio.ufba.br/ri/handle/ri/13837
Data do documento: 2006
Aparece nas coleções:Artigo Publicado em Periódico (Faculdade de Medicina)

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