https://repositorio.ufba.br/handle/ri/13706
Tipo: | Artigo de Periódico |
Título: | High prevalence of hepatitis B virus and hepatitis D virus in the western Brazilian Amazon. |
Título(s) alternativo(s): | American Journal of Tropical Medicine and Hygiene |
Autor(es): | Viana, Sebastião Paraná, Raymundo Moreira, Regina Célia Compri, Adriana Parise Macêdo, Vanize de Oliveira |
Autor(es): | Viana, Sebastião Paraná, Raymundo Moreira, Regina Célia Compri, Adriana Parise Macêdo, Vanize de Oliveira |
Abstract: | Severe cases of hepatitis caused by hepatitis B virus (HBV) or hepatitis D virus (HDV) are often seen in the Brazilian Amazon, but there is a paucity of epidemiologic studies on viral hepatitis in this area. Thus, a crosssectional study to investigate the prevalence of markers for HBV and HDV was performed. Serum samples were collected after participants completed an epidemiologic questionnaire. Markers for HBV and HDV were analyzed with an enzyme-linked immunosorbent assay. The HBV genotype was determined by sequencing of the gene for hepatitis B surface antigen (HBsAg). Of 2,656 samples, 89 (3.3%) were positive for HBsAg and 1,628 (61.5%) were positive for IgG antibody to hepatitis B core antigen.Markers for HDV were found in 47 cases (1.7%). Antibodies to HDV were associated with Amerindian ethnic origin, a lower educational level, a history of acute viral hepatitis, a history of malaria, male sex, a history of tattooing, and older age. The most frequent HBV genotypes were A and F. This study showed a high prevalence of HBV and HDV in the western Brazilian Amazon, as well as the predominance of HBV genotypes A and F. |
Tipo de Acesso: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/13706 |
Data do documento: | 2005 |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Arquivo | Descrição | Tamanho | Formato | |
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SEBASTIÃO VIANA.pdf | 236,66 kB | Adobe PDF | Visualizar/Abrir |
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