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dc.contributor.authorBittencourt, Achilea Candida Lisboa-
dc.contributor.authorLeite Primo, Janeusa Rita-
dc.contributor.authorBrites, Carlos-
dc.contributor.authorOliveira, Maria de Fátima Santos Paim de-
dc.contributor.authorCarvalho, Otávio Moreno-
dc.creatorBittencourt, Achilea Candida Lisboa-
dc.creatorLeite Primo, Janeusa Rita-
dc.creatorBrites, Carlos-
dc.creatorOliveira, Maria de Fátima Santos Paim de-
dc.creatorCarvalho, Otávio Moreno-
dc.date.accessioned2013-11-13T17:22:55Z-
dc.date.issued2005-
dc.identifier.issn1058-4838-
dc.identifier.urihttp://repositorio.ufba.br/ri/handle/ri/13631-
dc.descriptionTexto completo: acesso restrito.p.535-541pt_BR
dc.description.abstractBackground. Human T cell lymphotropic virus type 1 (HTLV-1)–associated infective dermatitis (IDH) is a chronic and recurrent eczema occurring during childhood and adolescence. HTLV-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic myelopathy of adulthood, presenting with slowly progressive spastic paraparesis and sphincter dysfunction with mild sensory involvement. There are few reports describing an association between IDH and HAM/TSP. The objective of this study was to evaluate the occurrence of HAM/TSP in patients with IDH and in seropositive members of their families and to determine the blood levels of antibodies against HTLV-1 in patients with HAM/TSP. Methods. Twenty patients with IDH and their seropositive mothers and siblings underwent clinical, neurological, and laboratory evaluations. The diagnosis of HAM/TSP was made in accordance with the World Health Organization criteria. Results. Nine individuals had HAM/TSP (6 of the patients with IDH, 2 mothers, and 1 seropositive brother). In 3 families, >1 individual had HAM/TSP. The serum antibody titers of the patients with HAM/TSP varied from 1 : 3.125 to 1 : 78.125. Conclusions. A strong association was observed between IDH and HAM/TSP. The familial clustering of both diseases suggests a genetic background. Serological screening for HTLV-1 in children with symptoms of myelopathy is essential in areas where HTLV-1 is endemic.pt_BR
dc.language.isoenpt_BR
dc.rightsAcesso Abertopt_BR
dc.sourcehttp://dx.doi.org/ 10.1086/432058pt_BR
dc.titleInfective Dermatitis and Human T Cell Lymphotropic Virus Type 1–Associated Myelopathy/Tropical Spastic Paraparesis in Childhood and Adolescencept_BR
dc.title.alternativeClinical Infectious Diseasespt_BR
dc.typeArtigo de Periódicopt_BR
dc.identifier.numberv. 41, n. 4pt_BR
dc.embargo.liftdate10000-01-01-
Aparece nas coleções:Artigo Publicado em Periódico (Faculdade de Medicina)

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