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Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/13567
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dc.contributor.authorSantos, Nicole R. S.-
dc.contributor.authorSantos, Jean Nunes dos-
dc.contributor.authorReis Junior, João A. dos-
dc.contributor.authorOliveira, Priscila C.-
dc.contributor.authorSousa, Ana Paula Cavalcanti de-
dc.contributor.authorCarvalho, Carolina Montagn de-
dc.contributor.authorSoares, Luiz Guilherme Pinheiro-
dc.contributor.authorMarques, Aparecida M. C.-
dc.contributor.authorPinheiro, Antonio Luiz Barbosa-
dc.creatorSantos, Nicole R. S.-
dc.creatorSantos, Jean Nunes dos-
dc.creatorReis Junior, João A. dos-
dc.creatorOliveira, Priscila C.-
dc.creatorSousa, Ana Paula Cavalcanti de-
dc.creatorCarvalho, Carolina Montagn de-
dc.creatorSoares, Luiz Guilherme Pinheiro-
dc.creatorMarques, Aparecida M. C.-
dc.creatorPinheiro, Antonio Luiz Barbosa-
dc.date.accessioned2013-11-06T20:19:47Z-
dc.date.issued2010-
dc.identifier.issn1549-5418-
dc.identifier.urihttp://repositorio.ufba.br/ri/handle/ri/13567-
dc.descriptionTexto completo: acesso restrito. p. 483-488pt_BR
dc.description.abstractObjective: The aim of this study was to assess and compare the effects of laser phototherapy (LPT) on cutaneous flaps on diabetic rats. Background: Diabetes mellitus is characterized by high blood glucose levels. Its main complications are delayed wound healing, an impaired blood supply, and a decrease in collagen production. Cutaneous flaps are routinely used in several surgical procedures, and most failures are related to poor blood supply. LPT has been studied using several healing models. Animals and Methods: Twelve Wistar rats were randomized into three groups: group 1 (G1; diabetic animals without treatment), group 2 (G2; diabetic animals irradiated with λ680 nm), and group 3 (G3; diabetic animals irradiated with λ790 nm). Diabetes was induced with streptozotocin. A 2- x 8-cm cutaneous flap was raised on the dorsum of each animal, and a plastic sheet was introduced between the flap and the bed to cause poor blood supply. Nonirradiated animals acted as controls. The dose per session was 40 J/cm2. Laser light was applied transcutaneously and fractioned on 16 contact points at the wound margins (16 × 2.5 J/cm2). Animal death occurred on day 8 after surgery. Specimens were taken, processed, cut, stained with eosin (HE) and sirius red, and underwent histological analysis. Results: It is shown that accute inflammation was mostly discrete for G3. Chronic inflammation was more evident for G2. Fibroblast number was higher for G3. Angiogenesis was more evident for G3. Necrosis was more evident for G2. Statistical analysis among all groups showed significant differences (p = 0.04) on the level of acute inflammation between G1 and G3, tissue necrosis between G1 and G2 (p = 0.03), chronic inflammation between (p = 0.04), fibroblastic proliferation between G2 and G3 (p = 0.05), and neovascularization between G2 and G3 (p = 0.04). Conclusion: LPT was effective in increasing angiogenesis as seen on irradiated subjects and was more pronounced when IR laser light was used.pt_BR
dc.language.isoenpt_BR
dc.rightsAcesso Abertopt_BR
dc.sourcehttp://dx.doi.org/10.1089/pho.2009.2500pt_BR
dc.subjectLaser Phototherapypt_BR
dc.subjectRatspt_BR
dc.subjectDiabetes Mellituspt_BR
dc.subjectAnimals laboratorypt_BR
dc.titleInfluence of the use of laser phototherapy (λ660 or 790nm) on the survival of cutaneous flaps on diabetic ratspt_BR
dc.title.alternativePhotomedicine and Laser Surgerypt_BR
dc.typeArtigo de Periódicopt_BR
dc.identifier.numberv. 28, n. 4pt_BR
dc.embargo.liftdate10000-01-01-
Aparece nas coleções:Artigo Publicado em Periódico (Faculdade de Odontologia)

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