https://repositorio.ufba.br/handle/ri/12789
Campo DC | Valor | Idioma |
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dc.contributor.author | Andreozzi, Valeska Lima | - |
dc.contributor.author | Bailey, Trevor | - |
dc.contributor.author | Nobre, Flavio Fonseca | - |
dc.contributor.author | Struchiner, Claudio Jose | - |
dc.contributor.author | Barreto, Mauricio Lima | - |
dc.contributor.author | Assis, Ana Marlucia de Oliveira | - |
dc.contributor.author | Santos, Leonor Maria Pacheco | - |
dc.creator | Andreozzi, Valeska Lima | - |
dc.creator | Bailey, Trevor | - |
dc.creator | Nobre, Flavio Fonseca | - |
dc.creator | Struchiner, Claudio Jose | - |
dc.creator | Barreto, Mauricio Lima | - |
dc.creator | Assis, Ana Marlucia de Oliveira | - |
dc.creator | Santos, Leonor Maria Pacheco | - |
dc.date.accessioned | 2013-09-02T14:55:07Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1047-2797 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/12789 | - |
dc.description | Texto completo: acesso restrito. p. 241–247 | pt_BR |
dc.description.abstract | Purpose: By adopting more appropriate and powerful statistical methods that fully exploit longitudinal structure, we reanalyze and extend previously published results from a large community trial to investigate the effect of vitamin A supplementation on the prevalence and severity of diarrhea in young children. Methods: Generalized linear mixed models were used to allow for repeated measures in a reanalysis of a double-blind, randomized, placebo-controlled community trial conducted in a cohort of children in northeastern Brazil during 1 year. The response variable was weekly number of days with diarrhea for each child, and Markov Chain Monte Carlo methods were used to estimate model parameters. Results and conclusions: Random effects suitably accounted for the underlying heterogeneity between and within children, and our longitudinal analysis shows a significant beneficial effect of vitamin A supplementation that was inconclusive in previously reported simple summary analyses of these data. Risk for diarrhea infection was estimated to be 1.57 times greater for a child administered a placebo as opposed to vitamin A (95% credible interval, 1.17–2.12). Additionally, we identified previously unreported temporal effects in these data, showing a decreasing daily probability of diarrhea for both groups during the trial and treatment–time interaction. | pt_BR |
dc.language.iso | en | pt_BR |
dc.source | http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.annepidem.2005.08.007 | pt_BR |
dc.subject | Diarrhea | pt_BR |
dc.subject | Vitamin A | pt_BR |
dc.subject | Longitudinal Randomized Trial | pt_BR |
dc.subject | Random Effects Models | pt_BR |
dc.title | Random-Effects Models in Investigating the Effect of Vitamin A in Childhood Diarrhea | pt_BR |
dc.title.alternative | Annals of Epidemiology | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v.16 n. 14 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (Escola de Nutrição) |
Arquivo | Descrição | Tamanho | Formato | |
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1-s2.0-S1047279705003200-main.pdf Restricted Access | 168,68 kB | Adobe PDF | Visualizar/Abrir Solicitar uma cópia |
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