https://repositorio.ufba.br/handle/ri/12746| metadata.dc.type: | Artigo de Periódico |
| Title: | Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline |
| Other Titles: | Australian Journal of Chemistry |
| Authors: | Silva, Michelli M. Bergamasco, Juliana Lira, Simone Possedente de Lopes, Norberto Peporine Hajdu, Eduardo Peixinho, Solange Berlinck, Roberto Gomes de Souza |
| metadata.dc.creator: | Silva, Michelli M. Bergamasco, Juliana Lira, Simone Possedente de Lopes, Norberto Peporine Hajdu, Eduardo Peixinho, Solange Berlinck, Roberto Gomes de Souza |
| Abstract: | In order to investigate the chemical profile of 14 specimens of Aplysina spp. marine sponges, we have developed a method based on LC-PDA-MS for the detection of bromotyrosine-derived metabolites. The method enabled the dereplication of three distinct chemotypes of bromotyrosine-derived compounds based on UV absorptions, which were further refined by electrospray ionization-mass spectrometry analysis of the brominated quasi-molecular ion clusters. This procedure led to either a single compound assignment, or a maximum of two possible isobaric compounds. The dereplication study indicated that the chemical profile of the 14 specimens of Aplysina spp. analyzed presented practically the same dibromotyrosine-derived compounds. The results obtained suggested a possible biogenetic pathway for the formation of dibromotyrosine-derived compounds of wide occurrence in Verongida sponges. |
| URI: | http://www.repositorio.ufba.br/ri/handle/ri/12746 |
| Issue Date: | 2010 |
| Appears in Collections: | Artigo Publicado em Periódico (Química) |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Michelli M. Silva.pdf Restricted Access | 512 kB | Adobe PDF | View/Open Request a copy |
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