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Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/11969
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dc.contributor.authorInês, Elizabete de Jesus-
dc.contributor.authorSilva, Mônica Lopes Sampaio-
dc.contributor.authorSouza, Joelma Nascimento-
dc.contributor.authorTeixeira, Márcia Cristina Aquino-
dc.contributor.authorSoares, Neci Matos-
dc.creatorInês, Elizabete de Jesus-
dc.creatorSilva, Mônica Lopes Sampaio-
dc.creatorSouza, Joelma Nascimento-
dc.creatorTeixeira, Márcia Cristina Aquino-
dc.creatorSoares, Neci Matos-
dc.date.accessioned2013-06-18T20:41:48Z-
dc.date.available2013-06-18T20:41:48Z-
dc.date.issued2013-
dc.identifier.issn0732-8893-
dc.identifier.urihttp://www.repositorio.ufba.br/ri/handle/ri/11969-
dc.descriptionTexto completo. Acesso restrito. p. 31-35pt_BR
dc.description.abstractCarbohydrates of pathogen antigens have been disrupted by periodate oxidation, in order to reduce nonspecific bindings and improve serodiagnosis of parasite infections. In the present study, the enzymelinked immunosorbent assay (ELISA) was carried out with filariform larvae antigen treated, or not treated, with sodium metaperiodate. Groups of sera from patients with Strongyloides stercoralis infection, with other intestinal parasites and a normal control, were used. The oxidation of Strongyloides stercoralis glycosylated epitopes reduced the seroreactivity of sera from patients with S. stercoralis infection as demonstrated by ELISA, with a decrease in sera optical densities. The number of cross-reactions of IgG and IgE-ELISAs increased by 12% and 16%, respectively, after antigen treatment with metaperiodate. This was more often observed in patients infected with Schistosoma mansoni and hookworm. Moreover, the IgG depletion from sera tested by IgE-ELISA led to the detection of previous false-negative samples from S. stercoralis–infected patients.pt_BR
dc.language.isoenpt_BR
dc.publisherDiagnostic Microbiology and Infectious Diseasept_BR
dc.sourcehttp://dx.doi.org/10.1016/j.diagmicrobio.2013.01.016pt_BR
dc.subjectStrongyloides stercoralispt_BR
dc.subjectSodium metaperiodatept_BR
dc.subjectSerodiagnosispt_BR
dc.subjectGlycoproteinspt_BR
dc.titleThe role of glycosylated epitopes in the serodiagnosis of Strongyloides stercoralis infectionpt_BR
dc.title.alternativeDiagnostic Microbiology and Infectious Diseasept_BR
dc.typeArtigo de Periódicopt_BR
dc.description.localpubSalvadorpt_BR
dc.identifier.numberv. 76, n. 1pt_BR
Aparece nas coleções:Artigo Publicado em Periódico (FAR)

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