Resumo:
We conducted a randomized trial to test an
intervention aimed at increasing adherence to antiretroviral therapy (ART) among HIV-positive, ART-naı¨ve patients in
Salvador, Brazil. Participants (N = 107) were randomized to either educational workshops based on the informationmotivation-
behavioral skills model (n = 52) or a control
video session (n = 55). Changes in self-reported ART adherence, viral load, CD4 cell counts and ART pharmacy
records were measured periodically over 12 months. After 3–6 months, ART adherence (C95%) was 77.8% in the workshop group and 85.7% in video group (as treated) and
53.8% and 65.5%, respectively, using intention-to-treat (ITT) analysis (both P[0.05) At 9–12 months, ART adherence decreased to 73.7% in the workshop group and
79.1% in the video group (as treated) and 53.8% and 61.8% using ITT, respectively. No differences were found in selfreported
adherence, viral load or pharmacy records
between groups. We found that the educational workshop intervention does not increase adherence to ART.
