Resumo:
Medicinal plants are sources of several biologically active compounds serving as raw materials
for herbal medicines and other medicines. This research carried out chemical and biological
prospecting of the species Carpotroche brasiliensis and Elaeocarpus serratus, occurring in
Bahia, with the aim of obtaining bioactive fixed and essential oils with biotechnological and
cosmetic applications. The species C. brasiliensis belonging to the Achariaceae family has an
oil extracted from the seed qith insecticidal and antiparasitic actions and E. serratus is
recognized for its antimicrobial action and is used in the treatment of diarrhea, rheumatism and
hair growt, these species being found in northeastern Brazil, particularly in Bahia. The oils were
obtained through extraction methods for fixed oils such as maceration, Soxhlet and for essential
oils Clevenger and evaluated through tests for antioxidant, cytotoxic, antimicrobial and
pediculicidal activity. The compositions of the oils were determined by direct injection gas
chromatography, infrared, thermal analysis. Bioactive oils have been subjected to the
development of emulsified systems that can improve the biological availability of active
substances. The galenic formulas obtained were also evaluated by physicochemical methods of
accelerated stability such as vortex exposure, centrifugation, in addition to monitoring pH and
organoleptic properties. Spreadability and viscosity tests were also carried out. In this way, the
research identified the obtaining of fixed oils and innovative pharmaceutical and cosmetic
products with pediculicidal properties, low values for acidity and high for the saponification
index as well as the presence of palmitic acid, demonstrating potential food use of the oil from
the seed of the E. serratus, oleic acid as a good natural emollient, helping skin permeability. In
addition to contributing to the functionality, chemical and biological knowledge of plant species
in Bahia.
