BACKGROUND: Visceral leishmaniasis (VL) is a neglected zoonosis that has considerable impacts on public health. One of the problems related to VL is the emergence of severe forms that lead to the death of 6-8% of patients, ...

Immune system disorders are responsible for the development of various diseases. The drugs used to treat these conditions have serious side effects, which creates the need for new pharmaceuticals. In this context, physalins ...

INTRODUCTION: Autism spectrum disorders (ASD) are a group of conditions that impact social interaction, communication, and behavior. In recent years, numerous mutations in various genes have been associated with ASD. Among ...

INTRODUCTION: Since its re-emergence in 2013, the chikungunya virus (CHIKV) has caused numerous outbreaks worldwide, particularly affecting Latin America and Brazil. The most common symptoms among infected individuals ...

INTRODUCTION: In addition to those traditionally recognized as the main risk factors for kidney disease, increasing emphasis has been placed on the genetic makeup of patients. OBJECTIVE: To estimate the frequency of risk ...

Introdução. A hemoglobina S (HbS) resulta da troca de nucleotídeo (GAG GTG) no sexto codon do gene da globina beta, levando à substituição do ácido glutâmico por valina na cadeia da globina beta. A anemia falciforme ou a ...