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|Title: ||Seroprevalence and risk factors associated with Helicobacter pylori infection in blood donors in Salvador, Northeast-Brazil|
|Other Titles: ||Brazilian Journal of Infectious Diseases|
|Authors: ||Lyra, André Castro|
Santana, Nelma Pereira de
Silvany Neto, Anibal
Pereira, Eduardo M.
Lyra, Marcos C.
Lyra, Luiz Guilherme Costa
|Keywords: ||H. pylori;seroprevalence;risk factors;Brazil|
|Issue Date: ||2003|
|Publisher: ||Brazilian Journal of Infectious Diseases|
|Abstract: ||Helicobacter pylori plays an important role in the etiology of peptic ulcer disease. Its
prevalence appears to be higher in developing countries. We evaluated the seroprevalence of
H. pylori and risk factors associated with infection in voluntary blood donors who attended
the main blood center of the city of Salvador, Brazil. The subjects responded to an
epidemiological questionnaire, with information about sex, age, race, lifestyle, social-economic
level indicators, and residence and hygiene conditions. Anti-H. pylori antibody was determined
by ELISA (Cobas Core, Roche). Three hundred and seven subjects were included in the study.
Anti-H. pylori antibody results were indeterminate in 33 individuals (10.8%), who were
excluded from analysis. Among the remaining 274 subjects, 187 (68.2%) were anti-H. pylori
positive. Based on multivariate logistic regression analysis three variables were found to be
significantly associated with a higher prevalence of H. pylori infection: absence of plumbing
in the residence during childhood, a history of rainwater invading the dwelling during
childhood, and low ingestion of milk.|
|Description: ||p. 339-345|
|Appears in Collections:||Artigos Publicados em Periódicos (Medicina)|
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