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Please use this identifier to cite or link to this item: http://repositorio.ufba.br/ri/handle/ri/5820

Title: Bone repair following bone grafting hydroxyapatite guided bone regeneration and infra-red laser photobiomodulation: a histological study in a rodent model
Other Titles: Lasers in Medical Science
Authors: Pinheiro, Antonio Luiz Barbosa
Gerbi, Marleny E. Martinez
Limeira Jr, Francisco de Assis
Ponzi, Elizabeth Arruda Carneiro
Marques, Aparecida M. C.
Carvalho, Carolina Montagn de
Santos, Rafael de Carneiro
Oliveira, Priscila Chagas
Noia, Manuela Pimentel
Ramalho, Luciana Maria Pedreira
Keywords: Bone regeneration;Laser biomodulation;Biomaterials;Hydroxyapatite;Membrane
Issue Date: 2009
Abstract: Abstract The aim of the investigation was to assess histologically the effect of laser photobiomodulation (LPBM) on a repair of defects surgically created in the femurs of rats. Forty-five Wistar rats were divided into four groups: group I (control); group II (LPBM); group III (hydroxyapatite guided bone regeneration; HA GBR); group IV (HA GBR LPBM). The animals in the irradiated groups were subjected to the first irradiation immediately after surgery, and it was repeated every day for 2 weeks.The animals were killed 15 days, 21 days and 30 days after surgery. When the groups irradiated with implant and membrane were compared, it was observed that the repair of the defects submitted to LPBM was also processed faster, starting from the 15th day. At the 30th day, the level of repair of the defects was similar in the irradiated groups and those not irradiated. New bone formation was seen inside the cavity, probably by the osteoconduction of the implant, and, in the irradiated groups, this new bone formation was incremental. The present preliminary data seem to suggest that LPMB therapy might have a positive effect upon early wound healing of bone defects treated with a combination of HA and GBR.
Description: Acesso restrito: Texto completo. p. 234-240
URI: http://www.repositorio.ufba.br/ri/handle/ri/5820
ISSN: 0268-8921
Appears in Collections:Artigos Publicados em Periódicos (Odontologia)

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