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Please use this identifier to cite or link to this item: http://repositorio.ufba.br/ri/handle/ri/3114

Title: Chronic periodontitis and C-reactive protein levels
Other Titles: J Periodontol
Authors: Gomes Filho, Isaac Suzart
Coelho, Julita Maria Freitas
Cruz, Simone Seixas da
Passos, Johelle Santana
Freitas, Camila Oliveira Teixeira de
Farias, Naiara Silva Aragão
Silva, Ruany Amorim da
Pereira, Milena Novais Silva
Lima, Thiago Lopes
Barreto, Mauricio Lima
Keywords: C-reactive protein;Inflammation;Myocardial Infarction;Periodontitis
Issue Date: 2011
Abstract: Background: This study aims to analyze the relationship between chronic periodontitis and C-reactive protein (CRP)by considering associated variables in individuals with or without cardiovascular disease. Methods: A sample of 359 individuals of both sexes (aged ‡40 years) was assessed. Among these individuals, 144 subjects were admitted to the hospital because of a first occurrence of acute myocardial infarction; 80 subjects were in the hospital for reasons other than acute myocardial infarction; and 135 subjects were living in the community. A questionnaire was applied to obtain demographic and lifestyle characteristics. Complete clinical periodontal examinations and anthropometric assessments were performed. CRP levels, plasma glucose levels, lipid profiles, and blood tests were performed to investigate any conditions that might have suggested infection and/or inflammation. CRP evaluations were performed using nephelometry. Individuals were considered to have periodontal disease if they simultaneously presented at least four teeth with one or more sites with probing depth ‡4mm, clinical attachment loss ‡3 mm, and bleeding on probing. Procedures for descriptive analyses and logistic regression were used. Results: In the chronic periodontitis group, mean CRP levels were higher than those in the group without chronic periodontitis (2.6 – 2.6 mg/L versus 1.78 – 2.7 mg/L, respectively). The final model showed that individuals with chronic periodontitis were more likely to have high CRP levels (adjusted odds ratio: 2.26; 95% confidence interval: 1.30 to 3.93) considering the effects of age, schooling level, sex, smoking, high-density lipoprotein cholesterol, and diabetes. Conclusion: In this study, chronic periodontitis is associated with elevated plasma CRP levels, even after controlling for several potential confounders.
URI: http://www.repositorio.ufba.br/ri/handle/ri/3114
ISSN: 0022-3492
Appears in Collections:Artigos Publicados em Periódicos Estrangeiros (ISC)

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