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Title: Pattern of asthma medication use among children from a large urban center in Brazil
Other Titles: Eur J Clin Pharmacol
Authors: Santos, Djanilson Barbosa
Alvaro, Alvaro A.
Simões, Silvia de Magalhães
Rodrigues, Laura C.
Camargos, Paulo Augusto Moreira
Coelho, Helena Lutescia Luna
Barreto, Mauricio Lima
Keywords: Asthma;Pharmacoepidemiology;Therapy;Children;Prevalence;Cross-sectional studies;Brazil
Issue Date: 2012
Abstract: Purpose Despite the advances in asthma therapeutics, there are few data on the use and determinants of anti-asthmatic drugs in the general population of children. This study describes the use of asthma medications among children in the general population and in children with current asthma, living in a large urban center in Brazil. Methods A population-based cross-sectional survey, aimed at analyzing asthma determinants, was conducted with 1,382 children aged 4–11 years, between February and May 2006, in Salvador, Brazil. At baseline, an extensive questionnaire was applied, including questions about the use of asthma medications in the last 12 months. Results In all studied children (n=1,382) aged 4–11 years, oral beta2-agonists were the drugs most frequently used (9.8%), followed by short-acting inhaled beta2-agonists (4.3%) and systemic corticosteroids (1.6%). Antiasthmatic drug use was higher among males than females, and it significantly decreased with age in both genders. A total of 312 children (22.6%) reported current asthma, and 62% of them were not being treated with any antiasthmatic drugs. Of all those who reported following a certain type of treatment, 20% used oral beta2-agonists alone; 6.1%, short-acting inhaled beta2-agonists alone; and 4.8%, a combination of both drugs. Anti-asthmatic drug use did not differ according to socioeconomic status,except for the use of inhaled beta2-agonists and systemic corticosteroids. Conclusions An overwhelming majority of asthmatic children were not using long-term medications for asthma, in particular inhaled corticosteroids, regardless of the severity of their disease. This result points to the deficiencies of the Brazilian public health system in recognizing this important pharmacological need for child care and thereby limiting the access of these children to a group of efficacious, available, and low risk therapeutic medications.
Description: Acesso ao texto completo: http://www.springerlink.com/content/l4uux73314054207/fulltext.pdf
URI: http://www.repositorio.ufba.br/ri/handle/ri/2896
ISSN: 0031-6970
Appears in Collections:Artigos Publicados em Periódicos Estrangeiros (ISC)

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