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Please use this identifier to cite or link to this item: http://repositorio.ufba.br/ri/handle/ri/14356

Title: Long lasting BCG protection against leprosy
Other Titles: Vaccine
Authors: Rodrigues, Laura Cunha
Kerr, Ligia Regina Franco Sansigolo
Frietas, Max Victor Carioca
Barreto, Mauricio Lima
Keywords: BCG vaccine;Leprosy;Waning of protection;Duration of protection;Vaccine efficacy
Issue Date: 2007
Abstract: Background: BCG vaccine protects against leprosy. Objectives: Estimate BCG protection against leprosy by age by age. Methods: A case control study with 226 cases of leprosy and 857 controls. BCG vaccination was ascertained via examination of BCG scars. Protection is presented for three age groups. Results: BCG protection against leprosy was 86% (95% CI: 77–92%) in the age group 18–29; 54% (95% CI: −37% to 85%) in the age group 30–39 and 32% (95% CI: −3% to 56%) in those aged 40 or more. Conclusions: BCG efficacy against leprosy may well last for three decades and possibly even longer. BCG vaccination must have contributed to worldwide reduction in leprosy incidence.
Description: Texto completo: acesso restrito. p. 6842-6844
URI: http://repositorio.ufba.br/ri/handle/ri/14356
ISSN: 0264-410X
Appears in Collections:Artigos Publicados em Periódicos Estrangeiros (ISC)

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