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Please use this identifier to cite or link to this item: http://repositorio.ufba.br/ri/handle/ri/13756

Title: Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load
Other Titles: Journal of Medical Virology
Authors: Almeida, Herbert
Vitvitski, Ludmila
Carmo, Theomira Mauadie Azevedo
Paraná, Raymundo
Reis, Mitermayer Galvão dos
Keywords: Hepatitis C;Saliva;Oral pathology
Issue Date: 2005
Abstract: Hepatitis C is a worldwide public health problem and its transmission is clearly associated with the parenteral route, however, the virus has also been isolated from other body fluids. Hepatitis C virus (HCV) RNA has been detected in saliva, yet the relationship between HCV and oral pathology is not clearly understood. Therefore, an investigation on HCV-RNA in saliva and its correlation with oral pathology was undertaken. Saliva and blood samples were collected from 50 anti-HCV positive patients and from 25 patients with non-HCV chronic liver disease. HCV-RNA was detected in all of the saliva samples from the HCV positive group. None of the saliva or serum samples from the non-HCV group were positive for HCV-RNA. The patients were examined for dental and oral health (dentate, partially dentate, edentulous, evidence of gum disease, or mucosal lesions); however, no correlation was found between HCV-RNA in saliva, oral health, and viral load. These results suggest that HCV-RNA presence in saliva is independent of the viral load and the oral pathology of HCV positive individuals. J. Med. Virol. 77:216–220, 2005. © 2005 Wiley-Liss, Inc.
Description: Texto completo: acesso restrito. p. 216–220
URI: http://repositorio.ufba.br/ri/handle/ri/13756
ISSN: 0146-6615
Appears in Collections:Artigos Publicados em Periódicos (Medicina)

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