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|Title: ||A mathematical model for the effect of anti-angiogenic therapy in the treatment of cancer tumours by chemotherapy|
|Other Titles: ||Nonlinear Analysis: Real World Applications|
|Authors: ||Pinho, Suani Tavares Rubim de|
Bacelar, F. S.
Andrade, Roberto Fernandes Silva
Freedman, H. I.
|Keywords: ||Differential equations model;Cancer therapy;Angiogenesis|
|Issue Date: ||2013|
|Publisher: ||Nonlinear Analysis: Real World Applications|
|Abstract: ||A model consisting of a system of five ordinary differential equations to simulate the
interactions between normal cells, cancer cells, endothelial cells, chemotherapy agent and
anti-angiogenic agent in tumour growth is developed. By a partial analysis of the cancerfree
subspace, it is shown how the anti-angiogenic agent may help the chemotherapy
agent in controlling the cancer. This is illustrated by numerical examples and bifurcation
|Description: ||Texto completo. Acesso restrito. p. 815–828|
|Appears in Collections:||Artigos Publicados em Periódicos (FIS)|
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