https://repositorio.ufba.br/handle/ri/7204
metadata.dc.type: | Artigo de Periódico |
Title: | HTLV-I associated myelopathy/tropical spastic paraparesis in a 7-year-old boy associated with infective dermatitis |
Other Titles: | Journal of the Neurological Sciences |
Authors: | Oliveira, Maria de Fátima Santos Paim de Bittencourt, Achilea Candida Lisboa Brites, Carlos Soares, George Hermes, Carrijo Almeida, Fabrício Oliveira |
metadata.dc.creator: | Oliveira, Maria de Fátima Santos Paim de Bittencourt, Achilea Candida Lisboa Brites, Carlos Soares, George Hermes, Carrijo Almeida, Fabrício Oliveira |
Abstract: | HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic myelopathy characterized by a slowly progressive spastic paraparesis and sphincter disturbances beginning in adulthood. Only eight well-documented cases occurring in childhood and adolescence have been described. Infective dermatitis associated to the HTLV-I (IDH) is a chronic eczema of childhood occurring in vertically infected carriers. Here we describe a 7-year-old boy with HAM/TSP and IDH. The neurological manifestations were spastic gait, hyperreflexia of lower limbs, clonus and bilateral Babinski’s sign. High levels of HTLV-I antibodies in the serum and in the cerebrospinal fluid were observed. The association of these two diseases and the early onset of HAM/TSP are probably related to a strong humoral anti-HTLV-I response. |
Keywords: | HTLV-I HAM/TSP Infective dermatitis Vertical transmission |
Publisher: | Elsevier |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/7204 |
Issue Date: | 2004 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
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