https://repositorio.ufba.br/handle/ri/6691
Tipo: | Artigo de Periódico |
Título: | Endocrine and metabolic disorders in HTLV-1 infected patients |
Título(s) alternativo(s): | Brazilian Journal of Infectious Diseases |
Autor(es): | Alves, Crésio de Aragão Dantas Dourado, Luciano |
Autor(es): | Alves, Crésio de Aragão Dantas Dourado, Luciano |
Abstract: | Human T-cell leukemia virus type 1 (HTLV-1) infection is endemic in Japan and several countries in South America, Caribbean and Africa. Endocrine and metabolic disorders have been variably reported to be associated with human T-cell leukemia virus type 1 (HTLV-1) infection. Therefore, the aim of this article was to critically evaluate the current knowledge of the endocrine and metabolic disorders associated with HTLV-1 infection. The literature search used PubMed, Web of Science, and LILACS databases in the past 10 years, utilizing, in various combinations, the following keywords: HTLV-1, adult T-cell leukemia, diabetes mellitus, GLUT-1, osteoporosis, hypercalcemia, autoimmune thyroid disorders, diabetes insipidus, inappropriate antidiuretic hormone secretion; pseudohypoparathyroidism; pseudopseudohypoparathyroidism. The proven endocrine manifestations of the HTLV-1 infection are calcium disorders which occur in some patients with acute HTLV-1/Adult T-cell leukemia/lymphoma. The few reports about thyroid, parathyroid, antidiuretic hormone and diabetes mellitus are insufficient to prove a causal association with HTLV-1 infection. The evidence for an association between endocrine disorders and HTLV-1 infection in general, and in asymptomatic patients is lacking. Given all these uncertainties, the endocrine expression of the HTLV-1 infection composes a promising research line for understanding the pathophysiology of this infection. |
Palavras-chave: | HTLV-1 Adult T-cell leukemia Endocrine disorders Metabolic disorders |
Editora / Evento / Instituição: | The Brazilian Journal of Infectious Diseases and Contexto Publishing |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/6691 |
Data do documento: | Nov-2010 |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Arquivo | Descrição | Tamanho | Formato | |
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Alves, Cresio.pdf | 750,75 kB | Adobe PDF | Visualizar/Abrir |
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