Campo DC | Valor | Idioma |
dc.contributor.author | Almeida, Roque Pacheco de | - |
dc.contributor.author | Vanet, Anne | - |
dc.contributor.author | Witko-Sarsat, Veronique | - |
dc.contributor.author | Melchior, Maxine | - |
dc.contributor.author | McCabe, Denise | - |
dc.contributor.author | Gabay, Joelle E. | - |
dc.creator | Almeida, Roque Pacheco de | - |
dc.creator | Vanet, Anne | - |
dc.creator | Witko-Sarsat, Veronique | - |
dc.creator | Melchior, Maxine | - |
dc.creator | McCabe, Denise | - |
dc.creator | Gabay, Joelle E. | - |
dc.date.accessioned | 2013-11-16T13:15:44Z | - |
dc.date.issued | 1996 | - |
dc.identifier.issn | 1046-5928 | - |
dc.identifier.uri | http://repositorio.ufba.br/ri/handle/ri/13682 | - |
dc.description | Texto completo. Acesso restrito. p. 355–366 | pt_BR |
dc.description.abstract | The azurophil granules of human PMN contain four antibiotic proteins, the serprocidins, which have extensive homology to one another and to serine proteases. Azurocidin, a member of this family, is a 29-kDa glycoprotein with broad spectrum antimicrobial activity and chemotactic activity toward monocytes. Insect cells transfected with a baculovirus vector carrying azurocidin cDNA produced a recombinant azurocidin protein. We purified the recombinant azurocidin protein from the culture medium of the infected cells and showed that it retained the antimicrobial activity of the native neutrophil-derived molecule. In addition, we present evidence that a 49-amino-acid region of the recombinant azurocidin protein is required for its secretion from insect cells. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | Protein Expression and Purification | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.source | http://ac.els-cdn.com.ez10.periodicos.capes.gov.br/S1046592896900534/1-s2.0-S1046592896900534-main.pdf?_tid=d9c95dfc-1977-11e3-9ca4-00000aab0f6b&acdnat=1378749009_93dac86784908821d1d8f4822de2bae0 | pt_BR |
dc.title | Azurocidin, a Natural Antibiotic from Human Neutrophils: Expression, Antimicrobial Activity, and Secretion | pt_BR |
dc.title.alternative | Protein Expression and Purification | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.description.localpub | Salvador | pt_BR |
dc.identifier.number | v. 7, n. 4 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina)
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