https://repositorio.ufba.br/handle/ri/20009 Mon, 04 May 2026 03:58:28 GMT 2026-05-04T03:58:28Z https://repositorio.ufba.br/handle/ri/32114 Título: A single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double‑blind, placebo study Autor(es): Toscano, Lydiane de Lima Tavares; Silva, Alexandre Sérgio; França, Ana Carla Lima de; Almeida Filho, Eder Jackson Bezerra de; Sousa, Bruno Rafael Virgínio de; Costa, Matheus da Silveira; Marques, Aline Telles Biasoto; da Silva, Darcilene Fiuza; Sena, Klécia de Farias; Cerqueira, Gilberto Santos; Gonçalves, Maria da Conceição Rodrigues Abstract: Purpose To investigate the effects of a single dose of juice on physical performance, oxidative stress, inflammation and muscle damage in runners. Methods Fourteen recreational male runners (39±9 years, VO2peak=55.9±6.5 ml/kg/min) performed two running tests to exhaustion at 80% of VO2max after ingesting grape juice or a placebo drink (10 ml/kg/day) randomly. Blood samples were taken before and 2 h after supplementation and immediately after running to analyze total antioxidant capacity (TAC), malondialdehyde (MDA), alpha-1 acid glycoprotein (A1GPA), high-sensitivity C-reactive protein (hs-CRP), creatine kinase (CK) and lactate dehydrogenase (LDH). Results The participants ran for an average of 59.2±27.8 min until exhaustion in the placebo group and for 68.4±29.7 min until exhaustion in the grape juice intake group, which was a significantly longer time (p=0.008). This improvement in physical performance was accompanied by a 43.6% increase in TAC (p=0.000) at the post-exercise timepoint compared to the level at baseline. MDA, A1GPA, hs-CRP, CK, and LDH did not exhibit changes. In contrast, no significant change in any variable was observed after consuming the placebo drink. Conclusion The single-dose intake of purple grape juice demonstrated an ergogenic effect in recreational runners by increasing run time to exhaustion and increasing antioxidant activity. Editora / Evento / Instituição: European Journal of Nutrition Tipo: Artigo de Periódico Fri, 15 Nov 2019 00:00:00 GMT https://repositorio.ufba.br/handle/ri/32114 2019-11-15T00:00:00Z