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Density of mast cells and microvessels in minor salivary gland tumors

2013-01-01T00:00:00Z

Título: Density of mast cells and microvessels in minor salivary gland tumors Autor(es): Vidal, Manuela Torres Andion; Araújo, Iguaracyra Barreto de Oliveira; Gurgel, Clarissa Araújo Silva; Pereira, Francisco De Assis Caldas; Vilas Bôas, Deise Souza; Ramos, Eduardo Antônio Gonçalves; Agra, Ivan Marcelo Gonçalves; Gonçalves, Ivan Marcelo; Freitas, Valéria Souza; Santos, Jean Nunes dos Abstract: The aim of this study was to investigate the density of mast cells and microvessels in minor salivary gland tumors. Forty-one cases of minor salivary gland tumors (pleomorphic adenoma, n = 10; adenoid cystic carcinoma, n = 11; mucoepidermoid carcinoma, n = 10; and polymorphous low-grade adenocarcinoma) were investigated using immunohistochemistry for mast cell tryptase and von-Willebrand factor. Density of mast cells was higher in mucoepidermoid carcinoma; however, no differences in the number of these cells were observed between the different types of tumors (p > 0.05). The number of mast cells was higher in periparenchymal areas in all tumors, but the difference was not significant (p > 0.05). Mucoepidermoid carcinoma showed the largest number of periparenchymal mast cells, whereas pleomorphic adenomas showed the smallest number of intraparenchymal mast cells (p > 0.05). The highest microvessel density was observed in mucoepidermoid carcinomas, being this difference statistically significant when mucoepidermoid carcinoma was compared to pleomorphic adenoma (p = 0.0034) and polymorphous low-grade adenocarcinoma (p = 0.004). Microvessel density was significantly higher in adenoid cystic carcinoma when compared to pleomorphic adenoma (p = 0.0406) and polymorphous low-grade adenocarcinoma (p = 0.0123). Comparison of mast cells and microvessel densities showed no significant difference between tumors. A quantitative difference in mast cells and microvessels was observed, particularly in mucoepidermoid carcinoma, a finding supporting the aggressive behavior of malignant salivary gland tumors without myoepithelial differentiation. Further studies are needed to determine the role of mast cells in angiogenesis, as well as in the development and biological behavior of these tumors. Tipo: Artigo de Periódico

Surgical prediction of skeletal and soft tissue changes in treatment of Class II

2013-01-01T00:00:00Z

Título: Surgical prediction of skeletal and soft tissue changes in treatment of Class II Autor(es): Lira, Ana de Lourdes Sá de; Moura, Walter Leal de; Artese, Flávia; Bittencourt, Marcos Alan Vieira; Nojima, Lincoln Issamu Abstract: Introduction: The purpose of this study was to study the treatment outcomes and the accuracy of digital prediction and the actual postoperative outcome with Dolphin program on subjects presenting Class II malocclusions. Methods Forty patients underwent surgical mandibular advancement (Group 1) and 40 underwent combined surgery of mandibular advancement and maxillary impaction (Group 2). The available pre surgical (t1) and a minimum of 12 months post surgical (t2) cephalometric radiographs were digitized. Predictive cephalograms (t3) for both groups were traced. Results At all times evaluated, Group 1 displayed a shorter mandibular length and Group 2 had a longer lower face. In both groups the surgical interventions (t2) were greater than initially predicted. There was no significant difference between groups with regards to overjet, overbite and soft tissue measurements. Conclusions In both groups surgeries were more extensive than planned. Facial convexity and the distance of the lips to cranial base presented similar values between t2 (post surgical) and t3 (predicted). Tipo: Artigo de Periódico

Influence of in vitro pigmenting of esthetic orthodontic ligatures on smile attractiveness

2012-01-01T00:00:00Z

Título: Influence of in vitro pigmenting of esthetic orthodontic ligatures on smile attractiveness Autor(es): Ferraz, Camila; Castellucci, Marcelo; Sobral, Márcio Costa Abstract: OBJECTIVE: To evaluate the perception of dental students and orthodontists on the degree of influence that pigmented esthetic elastic ligatures have on smile attractiveness, by judging clinical photographs. METHODS: Sixteen clinical facial photographs of the smile and 16 close up images of the smile of a single patient wearing monocrystalline porcelain orthodontic brackets, Teflon coated NiTi wire brackets and esthetic elastic ligatures of five different commercial brands were distributed into eight groups, G1 to G8 (Morelli®, Ortho Tecnology™, TP Orthodontics™, Unitek/3M™clear, Unitek/3M™ obscure, American Orthodontics™ clear, American Orthodontics™ pearl and American Orthodontics™ metallic pearl). Twenty ligatures were used in each group, totaling 160 ligatures. Half of them were used in their natural state, and the other half after in vitro pigmentation. All the photographs were judged by 40 evaluators, 20 orthodontists and 20 dental students. RESULTS: For orthodontists, American™ pearl (G7) ligatures were those that least influenced the degree of attractiveness of the smile in the two types of photographs used. For the dental students, in the facial photographs of the smile, ligatures with the best performance were Morelli® (G1), American™ clear (G6) and American™ pearl (G7) and in the close up photographs of the smile, American™ pearl, metallic pearl and clear (G7, G8 and G6). CONCLUSIONS: For both orthodontists and dental students, pigmentation of the elastic ligatures had a negative influence on the degree of attractiveness of smiles in the two types of clinical photographs evaluated. Tipo: Artigo de Periódico

Effects of LED phototherapy on bone defects grafted with MTA, bone morphogenetic proteins and guided bone regeneration: a Raman spectroscopic study

2012-01-01T00:00:00Z

Título: Effects of LED phototherapy on bone defects grafted with MTA, bone morphogenetic proteins and guided bone regeneration: a Raman spectroscopic study Autor(es): Pinheiro, Antonio Luiz Barbosa; Soares, Luiz Guilherme Pinheiro; Cangussu, Maria Cristina Teixeira; Santos, Nicole R. S.; Barbosa, Artur Felipe Santos; Silveira Júnior, Landulfo Abstract: We studied peaks of calcium hydroxyapatite (CHA) and protein and lipid CH groups in defects grafted with mineral trioxide aggregate (MTA) treated or not with LED irradiation, bone morphogenetic proteins and guided bone regeneration. A total of 90 rats were divided into ten groups each of which was subdivided into three subgroups (evaluated at 15, 21 and 30 days after surgery). Defects were irradiated with LED light (wavelength 850 ± 10 nm) at 48-h intervals for 15 days. Raman readings were taken at the surface of the defects. There were no statistically significant differences in the CHA peaks among the nonirradiated defects at any of the experimental time-points. On the other hand, there were significant differences between the defects filled with blood clot and the irradiated defects at all time-points (p < 0.001, p = 0.02, p < 0.001). There were significant differences between the mean peak CHA in nonirradiated defects at all the experimental time-points (p < 0.01). The mean peak of the defects filled with blood clot was significantly different from that of the defects filled with MTA (p < 0.001). There were significant differences between the defects filled with blood clot and the irradiated defects (p < 0.001). The results of this study using Raman spectral analysis indicate that infrared LED light irradiation improves the deposition of CHA in healing bone grafted or not with MTA. Tipo: Artigo de Periódico